Treatment of Amyloidosis
Treatment of all types of amyloidosis is currently based on the following principles:
- Reducing the supply of amyloid forming precursor proteins.
- Supporting the function of organs containing amyloid: In all types of amyloidosis, it is important that treatment should support the function of organs containing amyloid. In ATTR amyloidosis this may include:
- Treatment for heart disease
- Heart transplantation
- Treatment of peripheral neuropathy symptoms
- Treatment of autonomic neuropathy symptoms
- Liver transplantation as a treatment for hereditary ATTR amyloidosis - reducing the supply of amyloid precursor proteins
- AL Amyloidosis treatment includes chemotherapy
An important principle of treatment for cardiac amyloidosis is strict fluid balance control. Fluid excess can be avoided by careful attention to the 3 Ds: diet, diuretics and daily weights.